John Chrysostom
Upon appointing Saul as king, he was met with continual sorrows, one after another. When Saul disobeyed God's command by offering a sacrifice not sanctioned by Him, and when he defeated the Amalekites yet spared their king against divine instruction, Samuel's soul was deeply troubled. He never again saw Saul, and from that moment until his last day, he mourned and wept for him, despite being criticized for his profound sadness. The Lord spoke to him, asking, 'How long do you weep for Saul? For I have rejected him' (1 Sam. 16:1). If Samuel grieved over these occurrences, how much more sorrow must he have felt when Saul killed many innocent priests? Or when he sought to harm his benefactor, who had done him no wrong? When he witnessed Saul prophesying in a state of disarray?
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When he heard the many laments and grievances of David concerning Saul?
How deeply Samuel mourned, yet he could not save Saul. Are not the prayers of the saints ineffective? No, they possess immense strength, especially when combined with our own efforts.