Theophylact of Bulgaria
Together with Isaiah (Is 8:13), he commands us to sanctify the Lord in our hearts. That is, we must not exalt ourselves by visible works, but in the secret chamber of the heart perform the sanctification of the Lord.
This sanctification consists in withdrawal from defilements, that is, from the evil customs of the pagans. Sanctify Him in this way. He is sanctified through your good conduct, when other people glorify Him.
The God-man Himself commands the same: “Let your light so shine before men, that they may see your good works” (Mt 5:16).
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The words “ready to give an answer,” and so forth, must be joined with the words about showing good conduct, that is, having a good conscience. For when you do this with meekness and propriety, you yourselves will be assured that you have a good conscience.
You will also put to shame those who think evil of you.
The apostle commands the faithful man always to be ready to give an account of the faith. Whenever we are asked about the faith, we should always be able to answer readily, and to do this with meekness.
Everything, in general, should be done as if in the presence of God Himself. For in the presence of his master, no prudent servant is insolent.
The benefit of this is that unbelievers will learn what we are like and will be just toward us.
It should be observed that these words of the apostle do not contradict the saying of the Lord. When the Lord says that, when we are led before rulers and authorities, we should not be anxious about what to answer (Lk 21:14), He is speaking about witness.
The apostle Peter, however, is speaking about teaching. For whoever thinks that he knows something without understanding and examination brings blasphemy upon himself. The knowledge of the unwise consists of unexamined words.
Another explanation is this. Since we were accused of many transgressions, and our hopes were represented as vain, the apostle commands us to prepare thoughtful answers and to have a praiseworthy life. This he calls conscience.