Ambrosiaster writes: "With great impressiveness and far-reaching foresight the Apostle gives instructions to the pastor of the Church. For in his person lies the salvation of the whole flock. He speaks so strongly not out of anxiety about Saint Timothy, but about his successors. They must be guided by Saint Timothy's example and faithfully keep what their ordination obliged them to keep, handing down this example in themselves also to the successors who follow them."
"I charge you before God." "Again he calls God as witness, just as he did not long before this (cf. 5:21). At once he increases fear, makes his disciple steadfast, and reveals that these are not human ordinances. Thus Saint Timothy receives this commandment as though from the Lord Himself. By always keeping in mind the witness from whom he heard it, he shakes his soul by this remembrance" (Saint Chrysostom).
"Before God, who gives life to all things." The thought of God as everywhere present, sustaining all, and giving being and life to all gives the strongest impulse to moral energy. It enlivens the sense of complete dependence on God, upon which the fear of God is founded and by which it is nourished. This fear is the source of active wisdom.
If we recognize non-possessiveness as the subject of the charge, we may suppose that the reminder of God who gives life to all is given to awaken the conviction that man does not live by bread alone (cf. Mt 4:4). By this it removes the strongest support of concern for possessions, since such concern is chiefly sustained by fears for life when one has nothing.
"The Apostle speaks here as though saying: do not fear death, for you are the servant of God, who can give life to all" (Saint Chrysostom). If we recognize the subject of the charge as the faith of Christ in general, and zeal for spreading and maintaining it, then the reminder of God who gives life to all is given "as encouragement in the dangers connected with this. For if God gives life to all, why should we fear struggles for the faith?" (Oecumenius).
Perhaps the intention was also to lead the thought toward the future resurrection (cf. Saint Chrysostom, Blessed Theophylact) and to recall the word of the Lord: "He who believes in Me, though he die, yet shall he live" (cf. Jn 11:25). It is not inappropriate to admit this as the beginning of the following discourse, where the second coming of the Lord is mentioned.
"And before Christ Jesus, who witnessed the good confession before Pontius Pilate." This is the second reminder for arousing and strengthening moral energy. Christians live and breathe by Christ the Lord. Therefore remembrance of the Lord and Savior always calls forth the most stirring and life-giving thought. It is made here for this purpose.
"He also takes guiding instruction from the example of the Teacher. What he says has this meaning: as He acted, so, he says, you also must act. For He witnessed the good confession so that we might follow in His footsteps in this good confession. The Apostle suggests the same thing in the Epistle to the Hebrews, saying, 'Looking to Jesus, the author and finisher of faith, who for the joy set before Him endured the cross, despising the shame, and sat down at the right hand of the throne of God' (cf. Heb 12:2). And again: 'Consider Him who endured such contradiction from sinners against Himself, lest you grow weary in your souls' (cf. Heb 12:3)" (Saint Chrysostom).
But to what does such a reminder here stir us, and what does it present for imitation? Is it the good confession itself, that is, its content, or the unshaken courage with which it was given before the face of death? It is both.
The subject of the Lord's good confession is the assurance that He is the Son of God incarnate, who came to establish truth among men. Saint Chrysostom asks: "What does the Apostle here call the good confession of the Lord?" He answers: "That, when asked by Pilate, 'Are You then a king?' He answered, 'For this I was born, and for this I came into the world, to bear witness to the truth' (cf. Jn 18:37). Either he says this for that reason, or because, when asked whether He was the Son of God, He said, 'You say that I am' (Lk 22:70). Such witness was also given before Pilate, only not by word, but by not answering the question, or by silence, and then by the words spoken afterward (cf. Jn 19:7-11)."
Oecumenius directly understands the confession here as the fact that the Lord "testified that He is the Christ, the Son of God." But this is the essence of our faith, which accomplishes the salvation of men. Therefore Blessed Theodoret writes: "By the Lord's good confession the Apostle meant the salvation of the universe. For the Lord endured suffering for its salvation."
From this Ambrosiaster infers: "He recalls the suffering of Christ the Lord in order to instill fear, suggesting that the one who despises that for which Christ suffered must justly be recognized as guilty of that suffering."
After this, the Apostle's intention in recalling the good confession of Christ Jesus before Pilate may be expressed this way: confessing Christ Jesus as the Son of God, incarnate and suffering for our salvation, be ready yourself to endure everything, even death, for faith in Him and for life according to His Spirit. This is the same as what Saint Peter writes: "Since Christ therefore suffered for us in the flesh, arm yourselves also with the same mind" (1 Pet 4:1).
Applying this to the subject of the discourse, we see here the strongest motive for non-possessiveness, for fearless confession of the faith by word and deed, and for good pastoral ministry. Blessed Theodoret sees the last point here, writing: "The Apostle sets such testimony of Christ before his disciple as an example, so that he too may direct his disciples with greater zeal," fearlessly and tirelessly bearing witness before them and before all to the truth concerning Christ Jesus our Lord.