Jerome of Stridon
The straightforward implication is this: the serpent and the deceitful individual share a similarity; just as the serpent covertly stings and introduces venom, so does the slanderous person secretly defame and release the toxicity of his heart upon his neighbor, making him no better than the serpent itself. While the human tongue is intended for the blessing and uplifting of others, the one who commits slander equates himself with a serpent by misusing his abilities in a destructive manner.
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Conversely, if someone is subtly harmed by the serpent, the adversary, and unknowingly becomes tainted by sin's poison, then if the afflicted individual remains silent, refuses to repent, and does not confess his affliction to his brother or mentor, the brother or mentor, who possesses the words of healing, will be unable to assist him effectively. Just as a patient who feels shame in revealing their wound to a healer cannot be treated, so too does the art of healing fail for those who do not acknowledge their condition.