Gregory the Great
Verse 19. Neither his descendants shall be present, nor his lineage in the earth, nor a remnant within his domain (Job 18:19). For it is written: The Lord Jesus will bring him down by the Spirit of His mouth, and will annihilate him by the manifestation of His coming (2 Thess. 2:8). Thus, while his iniquity will cease with this age, ‘his descendants shall not endure,’ for he and his followers will face judgment; all the unrighteous, who have been led astray by his malevolence into sinful deeds, shall be struck down to eternal ruin by the brilliance of the Lord's return, along with their leader. There will be ‘none of his lineage remaining upon the earth,’ for the righteous Judge will terminate wickedness alongside the conclusion of this age. Furthermore, it is explicitly revealed that these statements pertain specifically to Antichrist, as he further elaborates: