Jerome of Stridon
A humble and unworthy individual shall ascend to a position of royal honor; however, after a brief time, he will meet his end, not due to popular discontent or wrathful emotions. This refers to Seleucus, known as Philopator, the son of Antiochus the Great, who failed to engage in deeds deserving of his father's dominion over Syria and died disgracefully, without any warfare. Porphyry contends that it was not Seleucus but Ptolemy Epiphanes who schemed against Seleucus and amassed an army against him, ultimately resulting in his poisoning by his own officials. When one of them inquired about the funds needed for such endeavors, he stated that his allies were his source of wealth.
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This revelation caused anxiety among the leaders, fearing he might seize their riches, leading to his treacherous demise. How could Ptolemy, who did not partake in these actions, ascend in the place of Antiochus the Great, especially since the Septuagint interpreters translated: and his offspring shall rise from his root, signifying his branch and lineage, indicating a blow to the prestige of the monarchy, and after a short time shall perish without conflict or battle? The Hebrews believe that the reference to the lowliest and most unworthy of royal glory pertains to Tryphon, who, acting as the guardian of Antiochus VI, known as Theos, wrongfully assumed tyrannical authority.