The Lord reassured Jacob with the promise: “into a great nation I will create you therein.” The unfolding of events demonstrated that Jacob's migration to Egypt would not obstruct the promise of a plentiful lineage. The Hebrews entered Egypt as 75 individuals (Genesis 46:27), but within 200 years, at the time of the exodus, their population would swell to 600,000, not counting their wives, children, elderly, and other members. The more the Egyptians afflicted them following Joseph’s death, the more they flourished through God's blessing (Ex. 1:12).
Moreover, Jacob may have been concerned about potential adversity or death during the arduous and lengthy journey ahead, particularly at his advanced age. The Lord reassured him by promising to accompany him to Egypt and to shield him from the hazards of the journey with His mighty protection: “I will go with you into Egypt.” Jacob might have contemplated how God’s assurance that his descendants would inherit the land of Canaan (Genesis 28:13-14) could come to pass if he left that territory for another. The Lord comforted him with the promise: “I will bring you up again,” meaning just as I will accompany you to Egypt, I will ultimately lead you back, through your descendants, to the land promised to you and your ancestors Abraham and Isaac. As for you personally, the Lord said, “Joseph shall lay his hands upon your eyes,” which means that although you will pass away in Egypt with your son Joseph by your side, take solace in the fact that it is not another who will provide you comfort in your final moments, but your cherished son, whom you believed to be lost.