Cyrill of Alexandria
From this, it is evident how astute the Apostle Paul was when he occasionally called upon those who were uplifted by faith in Christ for their salvation, urging them, "Awake, thou that sleepest" (Eph. 5:14). At times, he encourages enduring love in trials, as he reminds us, "But if you endure chastening, God deals with you as with sons; for what son is he whom the father chastens not?" (Heb. 12:7). This reflects God's compassionate nature, who, although He chastises sinners with reluctance, does so as a necessary means for their benefit.
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Just like physicians often prescribe potent remedies to heal their patients, inflicting discomfort to restore them to health, Paul warns of impending hardships and divine judgments, metaphorically "girding their jaws with bridle," as written (Psalms 31:9), urging them to embrace wisdom and turn toward what is virtuous and praiseworthy.
Thus, he admonishes, "Be sober, ye that drink wine." This counsel is directed at those who indulge to the point of intoxication, suggesting that had they recognized their folly sooner, they would have only needed the initial chastisement. Yet, when they failed to respond to earlier correction, further trials were imposed, often escalating in severity. However, even if belatedly, those who awaken to their senses and depart from their destructive impulses, akin to a mind shackled by drunkenness, are led to sincerely lament their transgressions. It is important to recognize that each of us harbors an intoxicating influence within our hearts, manifesting as various passions: one may chase after greed, another may be ensnared by worldly desires and pleasures, while others succumb to different forms of sin. We are all susceptible to harmful and ungodly inclinations—some more fervently than others.
Thus, the prophet advises, "Be sober, ye that are drunk with wine," encouraging those drowning in hedonism to grieve their condition since their longing for pleasure surpasses mere sufficiency, leading to excess and debauchery. From such individuals, he observes, joy and happiness are stripped away. Therefore, Christ rightly asserts, "Blessed are they that mourn," for they shall undoubtedly be comforted (Matt. 5:4). For those who indulge in luxuries, tears and sorrow become imperative, as the culmination of pleasure ultimately ends in lamentation, dragging those who are enamored with it toward despair. Furthermore, David aptly proclaims, "In death there is no remembrance of Thee" (Psalm 6:6), and similarly asserts, "The dead do not praise the LORD, nor any who go down into silence; but we will bless the LORD from this time forth and forevermore" (Psalm 113:25-26). This sentiment can also be applied to earthly experiences: when the sources of joy are stripped away by pests and misfortunes, the resulting despair robs victims of their happiness and vitality, often leading to severe emotional and physical tolls.