John Chrysostom
Peter had said, Be it far from thee, Lord, this shall not be unto thee; and had been answered, Get thee behind me, Satan; but the Lord was not satisfied with this rebuke, but over and above desired to shew the impropriety of those things which Peter had said, and the fruit of His own passion; whence it is added, Then said Jesus to his disciples, If any man will to come after me, let him deny himself, and take up his cross, and follow me; as much as to say, You say unto me, Be it far from thee; but I say unto you, that not only is it harmful for you to hinder Me from My Passion, but yourself will not be able to be saved unless you suffer and die, and renounce your life always.
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And note, that He does not speak of it as compulsory, for He does not say, Though ye will not yet must ye suffer this, but, If any man will. By saying this He rather attracted them; for he who leaves his auditor at liberty, attracts him the more; whereas he that uses violence oftentimes hinders him. And He proposes this doctrine, not to His disciples only, but in common to the whole world, saying, If any man will, that is, if woman, if man, if king, if free, if slave; there are three things mentioned; let him deny himself, take up his cross, and follow me.
Otherwise; He that disowns another, whether a brother, or a servant, or whosoever it be, he may see him beaten, or suffering aught else, and neither succours nor befriends him; thus it is he would have us deny our body, and whether it be beaten or afflicted in any other way, not to spare it. For this is to spare. So parents do then most spare their children when they hand them over to tutors, bidding them not to spare them. And that you should not think that this denial of self extends only to words or affronts, he shews to what degree we should deny ourselves, namely, to death the most shameful, even that of the cross; this He signifies when He says, And take up his cross, and follow me.
And because malefactors often suffer grievous things, that you should not suppose that simply to suffer evil is enough, He adds the reason of suffering, when He says, And follow me. For His sake you are to endure all, and to learn His other virtues; for this is to follow Christ aright, to be diligent in the practice of virtues, and to suffer all things for His sake.
And then because this seemed severe, He softens it by shewing the abundant rewards of our pains, and the punishment of evil, He that will save his life shall lose it.