John Chrysostom
What are you saying? You counted the kingdom and Gehenna as nothing in comparison with love for Christ. Did you then count human honor as something, so that you were exalted and needed continual restraint? He did not say, "that he might torment me in the future," but, "that he might torment me." Who could say this? What, then, do his words mean? When we show who this troubler is, and who the angel of Satan is, then we shall explain this also. Some said that he means a certain headache produced by the devil. But this cannot be accepted. Paul's body could not be given into the hands of the devil, if the devil himself yielded to that same Paul at a single command.
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Paul laid down laws and limits for him, for example when he delivered the fornicator to him for the destruction of the flesh (1 Cor 5:5). The devil did not dare transgress them. What, then, does what was said mean? In Hebrew, Satan means "adversary." Scripture in the Third Book of Kingdoms also gives this name to adversaries (3 Kgdms 5:4). Speaking of Solomon, it says, "There was no satan in his days," that is, no opponent who would fight against him or trouble him. Therefore the Apostle's words have this meaning: God was not pleased that our preaching should spread without hindrance, since He wished to humble our high opinion of ourselves. Rather, He permitted adversaries to attack us. This was indeed sufficient to cast down proud thoughts. A headache could not produce this. Thus, by the name angel of Satan, he means Alexander the coppersmith, the companions of Hymenaeus and Philetus, and all the adversaries of the word. They entered into contests with him and opposed him, cast him into prison, beat him, and dragged him about, since they were doing satanic works. Just as Scripture calls the Jews sons of the devil because they emulated his works, so it calls every opponent an angel of Satan. Therefore the words, "a thorn in the flesh was given to me to buffet me," do not mean that God Himself armed the adversaries, or punished and restrained the Apostle through them. Far be it. They mean only that He allowed and permitted it for a time.
"Lest I be exalted above measure," he says. For this reason God allowed the angels of Satan to torment me. By angels of Satan he means not demons, but people who serve the devil: unbelievers, tyrants, and pagans, who constantly pressed him and constantly persecuted him. The meaning of his words is this: God, as he says, could have stopped the continual persecutions and oppressions. But when I was caught up to the third heaven and raised into Paradise, He allowed these persecutions lest I become proud and haughty because of the greatness of these revelations. He permitted the angels of Satan to torment me with persecutions and afflictions, so that I would not be exalted above measure.