Theophylact of Bulgaria
Some explained this as follows: they will be destroyed in their own corruption, like irrational animals born naturally, that is, in no way differing from beasts born only for destruction. "Like irrational animals led by nature" means living by sense alone, and not by intellect or rational life. Therefore they are easily caught for a corrupt way of life. They are led and dragged along by anger and lust. They blaspheme what they do not know, that is, with their characteristic ignorance. Therefore they will be destroyed in the corruption they deserve, receiving the recompense for the lawlessness which they voluntarily prepared for themselves.