Andrew of Caesarea
The hail falling from heaven signifies the wrath of God descending from above. Its being as heavy as a talent signifies the fullness of wrath for the grave sins of men. The prophet Zechariah also saw a vision in a similar sense (Zech 5:7). Those struck by this hail will turn not to repentance, but to blasphemy. This bears witness to the hardness of their hearts, in which they become like Pharaoh (cf. Ex 4:21; 7:3; 9:12). This hardness will even exceed Pharaoh's. He was at least somewhat softened by the plagues and acknowledged his impiety, but they will blaspheme God even amid their punishments.