John Chrysostom
For this reason, He shall inherit many and strong ones, as it is proclaimed, for the love of Christ envelops us who consider this: if one died for all, then all died. And Christ died for all, so that those who live may no longer live for themselves but for the one who died for them and rose again (2 Cor. 5:14-15). Thus, none of us lives solely for himself (cf. Rom. 14:7), and you were redeemed at a great cost (1 Cor. 6:20); whether we live or die, we belong to the Lord (Rom. 14:8). Christ died for all, so that those who have life may no longer live for their own sake, but for Him who died and rose again on their behalf (2 Cor. 5:15). To clarify that the prophet’s words apply to both past and future, he states: He shall bear their iniquities (and their sins shall be borne by Him).
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According to Aquila, He will lift up. Symmachus translates it as He will lead. For this reason, He shall inherit many and share the spoils with the mighty (Therefore I will give Him a portion among the great, and with the strong He shall divide the spoil), referring to the spoils of Satan. He triumphed and seized the armor of the strong. It is aptly stated that He shall divide, for He granted tongues to some of His apostles while ordaining others. His soul was submitted to death and He was numbered with the transgressors (Because He delivered His soul unto death, and was numbered with the wicked). One translator observes, He was counted among the wicked. (He was delivered) unto death, not without purpose, but to raise them up. Can you perceive the benefit of death and the fruit of the cross? It is said that death was not equivalent because it fully aligned with His nature, as through His death He became the Sovereign of all who live. This death was marked by disgrace. The Jews recall, that deceiver, while He was still living, proclaimed, ‘After three days I will rise again’ (Matthew 27:63). It is rightly said: and with the lawless He was considered lawless, although He Himself was without lawlessness. He bore the transgressions of many and was offered up for their iniquities (whereas He bore the sin of many). Others declare, He accepted (and He became an intercessor for the transgressors). Aquila suggests: He went to meet those who mocked Him; Symmachus: those who opposed Him. Theodotion remarks: and He would have dealt with the wicked. Notice how the prophet consistently warns against causing anyone to stumble. How could a lawless man bear and remove the sins of others? Was it not for this reason that He suffered death, as He opposed sin? To eradicate sin, He willingly laid down His life. But why is it said that He lifted or will lift up? It signifies the cross, for on it sin was affixed; through the cross, sins were atoned.
The same prophet (Isaiah) also foretold that Christ would cast out demons from humanity: ‘and he will divide the spoils of the strong' (and with the strong he will divide the spoils) (Isaiah 53:12).