John Chrysostom
The Lord's purpose shall be fulfilled by His actions, as stated in Isaiah 53:10. Through the understanding of Him, My just Servant will bring justice to many. This reflects wisdom and insight, and knowing Him signifies resurrection. "He shall justify many" indicates He will reveal His righteousness. It is evident that as it is said, "by the knowledge of Him," the righteous is not his own, yet He will justify many, thus revealing righteousness to those previously unaware. The Lord's will will indeed be accomplished through His actions, as He adhered to the law of circumcision. He provided the symbol of His circumcision through the Lord, who took on the role of a servant, washing the feet of His disciples and drying them with a cloth. He was the Lord and Creator of those He humbly served.
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He did not come to be served, but to serve, as declared in Matthew 20:28. Furthermore, when questioned about who is greater, the one who reclines or the one who serves, He replied, "But I am among you as the one who serves," (Luke 22:27). This illustrates why He took on the form of a servant in order to serve many effectively. What do His words "by His hand" signify? Some interpret this as denoting the power of Christ's hand, emphasizing that His strength is derived from Himself rather than from any external source; whatever He willed, He accomplished through His own might. "Take away sorrows from His soul"—the faith of many somewhat alleviates His sorrows. Although He endured suffering for humanity, He still drew many to Himself. "And their sins He will bear upon Himself," for the righteous are never punished for sin.
The resurrection's power was prophesied by David, who declared that Christ would rise again: "For Thou wilt not leave my soul in hell, nor let Thy holy one see corruption" (Ps 15:10). Similarly, Isaiah expressed this truth in another manner: "He shall look on the deed of His soul with contentment; through the knowledge of Him My righteous Servant shall justify many, and bear their sins" (Is 53:11). In this way, Isaiah conveys that the sacrifice of Christ serves as the atonement for the transgressions of many.