John Chrysostom
In this context, the Lord does not regard as insignificant those who are genuinely humble, but rather those whom many perceive to be such—specifically, the impoverished, the marginalized, and the uninformed. How could anyone who holds greater value than the entire world be considered insignificant? They are friends of God. The Savior refers to those seen as small in the eyes of humanity. He mentions not many, but rather one, as a means to shield from numerous trials. Just as distancing oneself from evil is beneficial, so too is the honoring of the righteous. A prudent individual safeguards against wrongdoing in two ways: by separating from those who lead astray and by offering due respect and reverence to the holy.
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Moreover, further incentives are offered for honoring these individuals, as it is said, "As their angels are in heaven, they must see the face of my Father in heaven." This demonstrates that all saints have angels in the heavenly realm. As the Apostle states, a woman should possess the authority to have angels covering her head (1 Cor. 11:10), and Moses points out, "Set the bounds of tongues according to the number of the angels of God" (Deut. 32:8). The reference is not limited to angels alone but includes the higher orders of angels as well. When it is mentioned that they behold the face of My Father, it conveys their great boldness and significant honor.
Previously, angels were assigned according to the number of nations; however, now they are allocated based on the count of the faithful. This is affirmed by Christ's declaration, "See that ye despise none of these little ones: for I say unto you, that their angels in heaven always behold the face of my Father which is in heaven" (Matt. 18:10). Every believer is accompanied by an angel, just as every righteous person has had an angel since the dawn of time, as Jacob acknowledges: "The angel that delivereth me from all evil, let him bless these young men" (Genesis 48:16).