John Chrysostom
What is most grievous is that these wolves, he says, will arise "from among your own selves." This is especially grievous, when there is civil war within. He rightly said, "Watch," showing that the matter deserves special attention. It is the Church herself. A great danger threatens, since the Lord redeemed her with His blood. The battle will be great and twofold. He expressed this in the words, "From among your own selves men will arise, speaking perverse things, to draw away the disciples after themselves." After comforting them so that they would not grieve over his sufferings, and after saying that he endured them "with joy," he showed the fruits that came from them. Only then does he express the sorrowful thought. He does this so as not to burden their mind too heavily.
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What is this thought? It is this: "From among your own selves men will arise, speaking perverse things." Someone may say, "Do you think so much of yourself that, if you depart, we shall be deprived of life?" No, he says, I am not saying that my absence will have such consequences. What then? "From among your own selves" some men will arise. He did not say, "because of my departure," but "after my departure," that is, after my going away, as has already happened before. If it has happened until now, it will happen all the more afterward. Then the aim is shown: "to draw away the disciples after themselves." Thus heresies arise for no other purpose than this.